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The precursor of plaque rupture is known as thin cap fibroatheroma (TCFA). In the present study, the feasibility and accuracy of optical coherence tomography (OCT) for detecting the frequency and spatial distribution of TCFA was investigated ex vivo, and a 3-vessel OCT analysis was conducted to assess the feasibility of this modality in vivo.

circulation journal

Frequency and Spatial Distribution of Thin-Cap Fibroatheroma Assessed by 3-Vessel Intravascular Ultrasound and Optical Coherence Tomography An Ex Vivo Validation and an Initial In Vivo Feasibility Study