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Because many Japanese patients with hypercholesterolemia have received statin therapy for nearly a decade, there was a need to investigate the benefit of long-term treatment. The Japan Lipid Intervention Trial (J-LIT) Extension 10 study was planned to continue the original J-LIT study for a total of 10 years.

circulation journal

Relationship Between Coronary Events and Serum Cholesterol During 10 Years of Low-Dose Simvastatin Therapy Long-Term Efficacy and Safety in Japanese Patients With Hypercholesterolemia in the Japan Lipid Intervention Trial (J-LIT) Extension 10 Study, a Prospective Large-Scale Observational Cohort Study