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There is little information on the selection of antiarrhythmic agents for long-term prevention of paroxysmal atrial fibrillation (PAF). In the present study the preventive effects of pilsicainide (Pil) and cibenzoline (Cib) were compared in patients with PAF that was defibrillated at &lt;48 h or &gt;or=48 h after onset.

circulation journal

Randomized Crossover Study of the Long-Term Effects of Pilsicainide and Cibenzoline in Preventing Recurrence of Symptomatic Paroxysmal Atrial Fibrillation Influence of the Duration of Arrhythmia Before Therapy