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The hepatocyte growth factor (HGF) is a multifunctional cytokine with cardioprotective properties and potent myogenic activity for vascular endothelium. In patients after acute myocardial infarction, exercise training has the beneficial effects on cardiovascular adaptations. We hypothesized that exercise induces HGF production in those patients. If this hypothesis is correct, HGF production may be associated with clinical parameters of cardiovascular function.

circulation journal

Exercise-Induced Hepatocyte Growth Factor Production in Patients After Acute Myocardial Infarction-Its Relationship to Exercise Capacity and Brain Natriuretic Peptide Levels-