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begins decades before the onset of clinical symptoms, such as angina pectoris, myocardial infarction or stroke,1,2 and it is this preclinical lag phase that provides the opportunity for the presymptomatic detection of disease, the identification of high-risk subjects, and initiation of appropriate preventive strategies. 3 The most innovative imaging techniques currently used include vascular sonography, electron-beam and multislice computed tomography (CT), and magnetic resonance imaging (MRI). Noninvasive ultrasonography (US) has been used to detect early signs of atherogenesis, such as impaired endothelial function, increased arterial wall thickness and decreased arterial distensibility, as well as atherosclerotic lesions reflecting a more advanced state of disease.

Noninvasive Ultrasound Techniques for the Assessment of Atherosclerosis in Coronary Artery Disease