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Effects of styrene exposure on middle latency auditory-evoked potentials (MAEPs), which reflect the central auditory function, were investigated. As significant delay in latencies of No, Po, Na, and Pa components and in- creases in the peak to peak intervals of MAEPs, but not amplitudes, were observed in a dose-dependent manner. The present and our previous studies demonstrate that electrophysiological alterations occur before neuronal cell dam- age induced by styrene exposure. The present results suggested that styrene has a marked effect on the processing of auditory information related to MAEPs.

Changes in Middle Latency Auditory-Evoked Potentials of the Rat Exposed to Styrene.