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A novel Cu(II) and Zn(II) complexes of triazolo-quinoline derivatives were synthesized by in situ method and were characterized by the spectro-analytical methods and their pharmacological properties were evaluated. The compound C3 has exhibited promising anticonvulsant activity towards the electroshock induced seizures in Wistar rats and possesses low toxicity, providing a high safety profile.

chemical and pharmaceutical bulletin/chemical and pharmaceutical bulletin

Anticonvulsant Activity and Toxicity Evaluation of Cu&lt;sup&gt;II&lt;/sup&gt; and Zn&lt;sup&gt;II&lt;/sup&gt; Metal Complexes Derived from Triazole-Quinoline Ligands