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The solubility of pioglitazone hydrochloride in binary mixtures of polyethylene glycol 400 with ethanol, N-methyl-2-pyrrolidone, propylene glycol, and water at 25 degrees C are reported. The generated data are fitted to the Jouyban-Acree model and the mean relative deviations are 2.6%, 1.5%, 5.8%, and 7.4%, respectively for ethanol, N-methyl-2-pyrrolidone, propylene glycol, and water.

chemical and pharmaceutical bulletin/chemical and pharmaceutical bulletin

Solubility of Pioglitazone Hydrochloride in Binary Mixtures of Polyethylene Glycol 400 with Ethanol, Propylene Glycol, N-Methyl-2-pyrrolidone, and Water at 25 .DEG.C