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A new neolignan named "camellioside A" (1) has been isolated from the leaves and branches of Camellia amplexicaulis, along with seven known glycosides (2-8). Their structures were determined by a variety of spectroscopic analyses. Among them, compounds 2, 3, 4, and 6 significantly (p&lt;0.05) increased the alkaline phosphatase activity and the mineralization of the nodules of the MC3T3-E1 osteoblastic cells compared to those of the control.

New Neolignan Component from Camellia amplexicaulis and Effects on Osteoblast Differentiation