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Quinoline hexose analogs are expected to be useful as novel agents for treatment of chloroquine-resistant malaria. Here, we report preparation of 4-hydroxy quinoline-beta-glucosides from anilines in 4 steps.

Preparation of Quinoline Hexose Analogs as Novel Chloroquine-Resistant Malaria Treatments (1). Synthesis of 4-Hydroxyquinoline-.BETA.-glucosides