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Two new anti-allergic compounds, torososide B and torosachrysone 8-O-6"-malonyl gentiobioside were isolated from the seeds of Cassia torosa Cav., and their structures were established as physcion 8-O-beta-D-glucopyranosyl-(1--&gt;6)-beta-D-glucopyranosyl- (1--&gt;3)-beta-D-glucopyranosyl-(1--&gt;6)-beta-D-glucopyranoside and torosachrysone 8-O-beta-D-glucopyranosyl-(1--&gt;6)-6-malonyl beta-D-glucopyranoside on the basis of spectral and chemical evidence. Torososide B and torosachrysone 8-O-6"-malonyl gentiobioside were found to inhibit the release of leucotrienes from rat peritoneal mast cells induced by calcium ionophore A 23187.

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Antiallergic Agent from Natural Sources. 2. Structures and Leukotriene Release-Inhibitory Effect of Torososide B and Torosachrysone 8-O-6''-Malonyl .BETA.-Gentiobioside from Cassia torosa Cav.