English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Title compounds were prepared in 20-72% yields from the S-aklylation of pyridinium 1- [3-ethoxycarbonyl-1-[(methylthio)thiocarbonyl]]allylides with some alkyl halides, followed by the treatment of the resulting pyridinium salts with a base and then a dehydrogenating agent. In part of these reactions novel heterocycles, ethyl 1-cyano-3-(methylthio)thieno[3, 4-b]indolizine-9-carboxylates, were also formed. The oxidation of the title compounds with m-chloroperbenzoic acid gave the corresponding sulfoxides in moderate to good yields, which smoothly underwent Pummerer reactions on treatment with acetic anhydride. The bromination of the 3-vinyl group in the title compounds, followed by treatment of the resulting dibromo adducts with a base afforded ethyl 2-bromo-3-[2-(methylthio)indolizin-3-yl]acrylates, 3-[1-cyano-2-(methylthio)indolizin-3-yl]propiolates, and ethyl thieno[2, 3-b]indolizine-2-carboxylate depending upon the substrate used.

Preparation of New Nitrogen-Bridged Heterocycles. 48. Syntheses and Reactions of Ethyl 3-[2-(Methylthio)indolizin-3-yl]acrylate Derivatives.