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Antiviral activity-guided isolation studies on the leaves of Atalantia monophylla (ROXB.) CORR. (Rutaceae) led to the identification of pyropheophorbide a (1), a simple chlorin derivative, from the chloroform extract (fr. B) as a possible antiviral active principle against herpes simplex virus type 2 (HSV-2). Pyropheophorbide a methyl ester (2) was also isolated from the hexane extract (fr. A).

chemical and pharmaceutical bulletin/chemical and pharmaceutical bulletin

Isolation of Pyropheophorbide a from the Leaves of Atalantia monophylla (ROXB.) CORR. (Rutaceae) as a Possible Antiviral Active Principle against Herpes Simplex Virus Type 2.