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1H NMR spectroscopy has been used to demonstrate specific binding of rat 80S ribosomes to the major conformer of an antitumor bicyclic hexapeptidic glucoside, RA-XII, isolated from Rubia cordifolia, in a fast exchange process.

Conformational recognition of RA-XII by 80S ribosomes. A differential line broadening study in 1H NMR spectroscopy.