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A new antiallergic agent with thromboxane A2 antagonistic activity, KW4099, was synthesized by a simple method. Its optical resolution was accomplished with the use of (+)- or (-)-2,2'-(1,1'-binaphthyl)phosphoric acid as a resolving agent.

Synthesis and Optical Resolution of an Antiallergic Agent KW4099 with Thromboxane A2 Antagonistic Activity.