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Three new fasciculol esters, fasciculic acids A (1), B (2) and C (3), having potent calmodulin antagonistic activity were isolated from the toxic mushroom Naematoloma fasciculare (Fr.) Karst. Their structures were elucidated on the basis of spectral and chemical evidence.

Fasciculic acids A,B and C as calmodulin antagonists from the mushroom Naematoloma fasciculare.