Synthesis of 7.BETA.-((Z)-2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid (ceftizoxime), a new semisynthetic cephalosporin antibiotic. I. An improved method for the preparation of 7-amino-3-methylene- and 7-amino-3-hydroxycepham-4-carboxylic acid.
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