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From the dried herb of Actinostemma lobatum MAXIM. (Cucurbitaceae), four dammarane-type triterpene glycosides named actinostemmosides A, B, C and D were isolated and their structures were elucidated on the basis of chemical and spectral evidence. Actinostemmosides A, B and C were identified as 20-ƒ--ƒÀ-D-glucopyranosides of 3ƒÀ, 6ƒ¿, 20, 27 tetrahydroxy( 20S ) dammar 24ene, 3ƒÀ, 7ƒÀ, 20, 27tetrahydroxy-(20S) -dammar-24-ene and 3ƒÀ, 7ƒÀ, 18, 20,27 -pentahydroxy-(20S) -dammar24-ene, respectively, and actinostemmoside D, as the ƒ¿Lrhamnopyranosyl(1• ̈2)ƒÀDgluco-

chemical and pharmaceutical bulletin/chemical and pharmaceutical bulletin

Studies on the constituents of Actinostemma lobatum Maxim. I Structures of actinostemmosides A, B, C and D, dammarane triterpene glycosides isolated from the herb.