English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The carba (2) and oxa analogues (3) of 2- (phenylpiperazinylalkoxyphenyl) thiazolidine-3-carboxamide (1, Y=O) and-thiocarboxamide (1, Y=S) were synthesized and tested for cardiotonic activity. These analogues (2 and 3) were prepared from the aldehydes (4) through several intermediates (7, 10, and 13). In a series of the N-methylcarboxamides, positive inotropic activity in anesthetized dogs decreased in the following order : the thiazolidine (1a) >>oxazolidine (3a) >pyrrolidine (2a). In the corresponding thiocarboxamide series, however, the oxazolidine (3b) was the most potent, followed by the thiazolidine (1b) and the pyrrolidine (2c).

chemical and pharmaceutical bulletin/chemical and pharmaceutical bulletin

Synthesis of 2-phenylthiazolidine derivatives as cardiotonic agents. V. Modification of the thiazolidine moiety of 2-(phenylpiperazinylalkoxyphenyl)thiazolidine-3-thiocarboxamides and the corresponding carboxamides.