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Curcumin is a wide-spectrum cellular protector with antiinflammatory, antioxidizant, and antifibrotic effects. This study was conducted to investigate its effects on myocardial collagen remodeling in pressure overloaded rabbits.

biological and pharmaceutical bulletin

Curcumin Ameliorates Left Ventricular Function in Rabbits with Pressure Overload: Inhibition of the Remodeling of the Left Ventricular Collagen Network Associated with Suppression of Myocardial Tumor Necrosis Factor-.ALPHA. and Matrix Metalloproteinase-2 Expression