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In a multi-stratum factorial experiment, there are multiple error terms (strata) with different variances that arise from complicated structures of the experimental units. For unstructured experimental units, minimum aberration is a popular criterion for choosing regular fractional factorial designs. One difficulty in extending this criterion to multi-stratum factorial designs is that the formulation of a wordlength pattern based on which minimum aberration is defined requires an order of desirability among the relevant words, but a natural order is often lacking. Furthermore, a criterion based only on wordlength patterns does not account for the different stratum variances. Mitchell, Morris, and Ylvisaker (1995) proposed a framework for Bayesian factorial designs. A Gaussian process is used as the prior for the treatment effects, from which a prior distribution of the factorial effects is induced. This approach is applied to study optimal and efficient multi-stratum factorial designs. Good surrogates for the Bayesian criteria that can be related to wordlength and generalized wordlength patterns for regular and nonregular designs, respectively, are derived. A tool is developed for eliminating inferior designs and reducing the designs that need to be considered without requiring any knowledge of stratum variances. Numerical examples are used to illustrate the theory in several settings.

A Bayesian approach to the selection of two-level multi-stratum factorial designs