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# {#article-title-2} To the Editor: We read the Editorial “Chronic cerebrospinal venous insufficiency: Have we found the cause and cure of MS?” 1 in response to our article.2 Drs. Fox and Rae-Grant reported that we used a single, unblinded ultrasound technician to study 499 subjects. This may be misleading to readers.We reported that blinding between the groups was achieved by the following strategies: 1) instructing subjects not to reveal their disease status during the examination; 2) including patients with no disability or walking difficulties to ensure blinding between nondisabled patients and both healthy and nonhealthy controls; 3) including patients with substantial disability, but no multiple sclerosis (MS) diagnosis who presented with gait disturbances and incoordination, dysarthria, and memory problems similar to patients with MS; and 4) using an ultrasound technologist unfamiliar with the signs and symptoms of either MS or other neurologic diseases.2 The effectiveness of these blinding methods can be debated but characterizing the technician …