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Manjunath et al.1 performed a cost analysis related to patients with epilepsy and found that those with uncontrolled epilepsy who required an emergency department (ED) visit or hospitalization posed clinical and economic burdens to health care providers and to society. We conducted a prospective study to analyze the burden of epilepsy at a regional hospital. In an attempt to develop a hypothetical prediction model, we evaluated factors associated with ED access by patients with an already-known diagnosis of epilepsy after a new seizure episode. In our analysis, we focused on direct health care costs by constructing a logistic model to predict ED visit. Factors related to ED visit were nationality, current psychiatric therapy, current antiepileptic drug polytherapy, comorbidities, recurrent same-day epileptic seizures, and seizure characteristics. A care model—based on knowledge of these predictive factors—could help to reduce the economic burden of uncontrolled epilepsy. In an era of increasing health care costs and shrinking resources, economic studies applied to health services are vital to increasing the awareness of how epilepsy affects individuals and society.2

Burden of uncontrolled epilepsy in patients requiring an emergency room visit or hospitalization