Age at Seroconversion, HLA Genotype, and Specificity of Autoantibodies in Progression of Islet Autoimmunity in Childhood | Zendy

Witold Bauer | Zendy; Riitta Veijola | Zendy; Johanna Lempainen | Zendy; Minna Kiviniemi | Zendy; Taina Härkönen | Zendy; Jorma Toppari | Zendy; Mikael Knip | Zendy; Attila Gyenesei | Zendy; Jorma Ilonen | Zendy

Open Access

Age at Seroconversion, HLA Genotype, and Specificity of Autoantibodies in Progression of Islet Autoimmunity in Childhood

Author(s) -

Witold Bauer,

Riitta Veijola,

Johanna Lempainen,

Minna Kiviniemi,

Taina Härkönen,

Jorma Toppari,

Mikael Knip,

Attila Gyenesei,

Jorma Ilonen

Publication year - 2019

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2019-00421

Subject(s) - autoantibody , autoimmunity , seroconversion , medicine , immunology , type 1 diabetes , human leukocyte antigen , diabetes mellitus , islet , insulin , endocrinology , antibody , antigen

Children with initial autoantibodies to either insulin (IAA) or glutamic acid decarboxylase (GADA) differ in peak age of seroconversion and have different type 1 diabetes (T1D) risk gene associations, suggesting heterogeneity in the disease process.

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