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Peptide receptor radionuclide therapy (PRRT) is an effective treatment of certain patients with metastatic neuroendocrine tumors (NETs). Tumor response is highly variable; no biomarker in clinical practice has been demonstrated to reliably predict outcome. The inflammation-based index (IBI), derived from serum C-reactive protein and albumin levels, predicts survival and response to treatment in patients in several cancer types and was therefore explored in this setting.

The Inflammation-Based Index Can Predict Response and Improve Patient Selection in NETs Treated With PRRT: A Pilot Study