Open AccessReduced Levels of Anti-Ageing Hormone Klotho Predict Renal Function Decline in Type 2 Diabetes
Author(s) -
Nikolaos Fountoulakis,
Giuseppe Maltese,
Luigi Gnudi,
Janaka Karalliedde
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-00004
Subject(s) - medicine , renal function , hazard ratio , interquartile range , endocrinology , gastroenterology , confidence interval
Soluble Klotho (sKlotho) is a circulating hormone with cardiovascular-renal protective effects. Whether sKlotho predicts estimated glomerular filtration rate (eGFR) decline in patients with type 2 diabetes mellitus (T2DM) with relatively preserved renal function is unknown.
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