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The pathophysiological role of gut incretin hormone argumentation on acute insulin release in the genesis of type 2 diabetes (TDM2) is uncertain. We examined retrospectively at 0 year and 10 years the endogenous incretin hormone action (IHA) on acute insulin release and glucose tolerance in normoglycemic relatives (REL) of TDM2 and control (CON) subjects.

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

Endogenous Incretin Hormone Augmentation of Acute Insulin Secretion in Normoglycemic Relatives of Type 2 Diabetic Subjects: A 10-Year Retrospective Pathophysiological Study