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Insulin is an important osteotropic hormone but may be negatively associated with bone mass after adjustment for body mass index in adolescent populations. However, the association between insulin and bone mass in adults remains unclear.

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

Insulin Is Inversely Associated With Bone Mass, Especially in the Insulin-Resistant Population: The Korea and US National Health and Nutrition Examination Surveys