Open AccessIncreased Placental Expression of Fibroblast Growth Factor 21 in Gestational Diabetes Mellitus
Author(s) -
Marloes Dekker Nitert,
Helen L. Barrett,
Marta H. Kubala,
Katherin Scholz Romero,
Kerina J. Denny,
Trent M. Woodruff,
David McIntyre,
Leonie Callaway
Publication year - 2014
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2581
Subject(s) - fgf21 , endocrinology , medicine , placenta , gestational diabetes , glut4 , receptor , glut1 , fibroblast growth factor , biology , fetus , glucose transporter , insulin , gestation , pregnancy , genetics
Fibroblast growth factor 21 (FGF21) can regulate glucose and lipid metabolism. The placenta actively synthesizes and secretes many hormones, but it is unknown whether this includes FGF21. This study aimed to analyze the placental expression of FGF21 in women with or without gestational diabetes mellitus (GDM).
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