Open AccessFas andFasLExpression in Human Adipose Tissue Is Related to Obesity, Insulin Resistance, and Type 2 Diabetes
Author(s) -
Matthias Blüher,
Nora Klöting,
Stephan Wueest,
Eugen J. Schoenle,
Michael P. Schön,
Arne Dietrich,
Mathias Faßhauer,
Michael Stümvoll,
Daniel Konrad
Publication year - 2013
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2013-2488
Subject(s) - insulin resistance , adipose tissue , fas ligand , medicine , obesity , type 2 diabetes , endocrinology , insulin , diabetes mellitus , type 1 diabetes , biology , apoptosis , genetics , programmed cell death
Deletion of the death receptor Fas (CD95) in adipocytes of mice is associated with improved insulin sensitivity and reduced adipose tissue (AT) inflammation.
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