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An impaired Na and water excretion rate during daytime is associated with increased cardiovascular risk factors. Recent findings suggest that disturbed circadian rhythms may play an important role in salt-sensitive hypertension and reduced β-cell function.

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

Reduced Insulin Secretion and Nocturnal Dipping of Blood Pressure Are Associated with a Disturbed Circadian Pattern of Urine Excretion in Metabolic Syndrome