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Testosterone (T) is excreted in urine as water-soluble glucuronidated and sulfated conjugates. The ability to glucuronidate T and other steroids depends on a number of different glucuronidases (UGT) of which UGT2B17 is essential. The aim of the study was to evaluate the influence of UGT2B17 genotypes on urinary excretion of androgen metabolites in pubertal boys.

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

A Common Deletion in the Uridine Diphosphate Glucuronyltransferase (<i>UGT</i>)<i>2B17</i>Gene Is a Strong Determinant of Androgen Excretion in Healthy Pubertal Boys

A Common Deletion in the Uridine Diphosphate Glucuronyltransferase (UGT)2B17Gene Is a Strong Determinant of Androgen Excretion in Healthy Pubertal Boys