Impact of Genetic Ancestry on Outcomes in ECOG-ACRIN-5103 | Zendy

Bryan P. Schneider | Zendy; Fei Shen | Zendy; Guanglong Jiang | Zendy; Anne O’Neill | Zendy; Milan Radovich | Zendy; Lang Li | Zendy; Laura Gardner | Zendy; Dongbing Lai | Zendy; Tatiana Foroud | Zendy; Joseph A. Sparano | Zendy; George W. Sledge | Zendy; Kathy D. Miller | Zendy

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Impact of Genetic Ancestry on Outcomes in ECOG-ACRIN-5103

Author(s) -

Bryan P. Schneider,

Fei Shen,

Guanglong Jiang,

Anne O’Neill,

Milan Radovich,

Lang Li,

Laura Gardner,

Dongbing Lai,

Tatiana Foroud,

Joseph A. Sparano,

George W. Sledge,

Kathy D. Miller

Publication year - 2017

Publication title -

jco precision oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.405

H-Index - 22

ISSN - 2473-4284

DOI - 10.1200/po.17.00059

Subject(s) - medicine , bevacizumab , breast cancer , context (archaeology) , clinical endpoint , randomized controlled trial , oncology , anthracycline , cancer , chemotherapy , paleontology , biology

Racial disparity in breast cancer outcomes exists between African American and Caucasian women in the United States. We have evaluated the impact of genetically determined ancestry on disparity in efficacy and therapy-induced toxicity for breast cancer patients in the context of a randomized, phase III adjuvant trial.

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