Open AccessVariability of Lung Tumor Measurements on Repeat Computed Tomography Scans Taken Within 15 Minutes
Author(s) -
Geoffrey R. Oxnard,
Binsheng Zhao,
Camelia S. Sima,
Michelle S. Ginsberg,
Leonard P. James,
Robert A. Lefkowitz,
Pingzhen Guo,
Mark G. Kris,
Lawrence H. Schwartz,
Gregory J. Riely
Publication year - 2011
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2010.33.7071
Subject(s) - medicine , lung cancer , context (archaeology) , lesion , nuclear medicine , lung , response evaluation criteria in solid tumors , radiology , clinical significance , computed tomography , chemotherapy , surgery , progressive disease , pathology , paleontology , biology
We use changes in tumor measurements to assess response and progression, both in routine care and as the primary objective of clinical trials. However, the variability of computed tomography (CT) -based tumor measurement has not been comprehensively evaluated. In this study, we assess the variability of lung tumor measurement using repeat CT scans performed within 15 minutes of each other and discuss the implications of this variability in a clinical context.
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