Open AccessImpact of the Duration of Adjuvant Hormonal Therapy in Patients With Locally Advanced Prostate Cancer Treated With Radiotherapy: A Secondary Analysis of RTOG 85-31
Author(s) -
Luís Souhami,
Kyounghwa Bae,
Miljenko V. Pilepich,
Howard M. Sandler
Publication year - 2009
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2008.17.4052
Subject(s) - medicine , hormonal therapy , radiation therapy , prostate cancer , proportional hazards model , hormone therapy , oncology , prostatectomy , androgen deprivation therapy , adjuvant , cancer , breast cancer
Radiation Therapy Oncology Group 85-31 was a randomized trial of androgen suppression for life for patients with locally advanced prostate cancer. However, not all patients continued on the protocol-mandated long-term hormonal therapy despite no evidence of recurrence. We correlated duration of adjuvant hormonal therapy and outcomes among patients who prematurely discontinued hormonal therapy.
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