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Welcome to this special issue of CBE—Life Sciences Education! The national scientific and academic community has issued repeated clarion calls for revising college biology curricula and the mathematical and computational preparation for future life scientists to reflect the tools and practices of science. This issue celebrates progress on incorporating quantitative reasoning into biology courses and integrating biological exemplars into mathematics courses. Within the 17 articles, seven essays, and seven features, readers find examples of innovative undergraduate research programs that emerged from research collaborations between biologists and mathematicians as well as collaborations initiated by either biologists or mathematicians. Other articles and essays illustrate collaborations between biologists and quantitative scientists that have resulted in new courses, new majors, textbooks, and modules that highlight and celebrate progress toward the BIO2010 vision.

Beyond BIO2010: Integrating Biology and Mathematics: Collaborations, Challenges, and Opportunities