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Background The purpose of this study is to assess the role of 18 fluorodeoxyglucose positron emission tomography/computed tomography ( 18 FDG PET-CT) in the follow-up of patients with lymphoma after finishing therapy. Results This study included 42 lymphomas (25 non-Hodgkin’s lymphoma and 17 Hodgkin’s lymphoma); patients ranging in age from 18 to 70 years were examined by 18 FDG PET-CT after therapy and analyzed retrospectively. Confirmatory biopsy was mandatory in cases of suspected disease recurrence and follow-up in cases of complete metabolic response. Positron emission tomography/computed tomography in assessment of lymphoma treatment response reveals significant statistical significance ( P < 0.05). It shows 100% sensitivity, 92.8% specificity, and 95.2% accuracy in the prediction of response. Conclusion Positron emission tomography/computed tomography plays an important role in detection of response to treatment of lymphoma after finishing therapy.

Lugano classification: response evaluation criteria for positron emission tomography/computed tomography in lymphoma follow-up