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Background Carpal tunnel syndrome is the commonest entrapment neuropathy. The cut-off point of cross-sectional area to diagnose carpal tunnel syndrome may vary among populations. The objective of this study was to determine the best cut-off point of median nerve cross-sectional area to diagnose carpal tunnel syndrome among Egyptian population and to compare the difference of median nerve cross-sectional area in diabetic patients versus healthy individuals. Results Mean cross-sectional area was 7.78 ± 1.260 mm 2  among healthy individuals and 8 ± 1.018 mm 2  among diabetics. Cut-off cross-sectional area of median nerve above which compression is anticipated is 9.5 mm 2 . Conclusion Ultrasound can be used to diagnose carpal tunnel syndrome by measuring the median nerve cross-sectional area.

High-resolution neuromuscular ultrasound-based diagnosis of carpal tunnel syndrome in a sample of Egyptian population