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Acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) is associated with high mortality in critically ill patients. However, the optimal timing to initiate CRRT in patients with AKI is unknown. The purpose of this study is to investigate whether the timing of initiation of CRRT according to severity of AKI is associated with in-hospital mortality.

renal replacement therapy

The optimal timing of continuous renal replacement therapy according to the modified RIFLE classification in critically ill patients with acute kidney injury: a retrospective observational study