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The genetic platforms of  Deinococcus  species remain the only systems in which massive ionizing radiation (IR)-induced genome damage can be investigated in vivo at exposures commensurate with cellular survival. We report the whole genome sequence of the extremely IR-resistant rod-shaped bacterium  Deinococcus ficus  KS 0460 and its phenotypic characterization.  Deinococcus ficus  KS 0460 has been studied since 1987, first under the name  Deinobacter grandis , then  Deinococcus grandis . The  D. ficus  KS 0460 genome consists of a 4.019 Mbp sequence (69.7% GC content and 3894 predicted genes) divided into six genome partitions, five of which are confirmed to be circular. Circularity was determined manually by mate pair linkage. Approximately 76% of the predicted proteins contained identifiable Pfam domains and 72% were assigned to COGs. Of all  D. ficus  KS 0460 proteins, 79% and 70% had homologues in  Deinococcus radiodurans  ATCC BAA-816 and  Deinococcus geothermalis  DSM 11300, respectively. The most striking differences between  D. ficus  KS 0460 and  D. radiodurans  BAA-816 identified by the comparison of the KEGG pathways were as follows: (i)  D. ficus  lacks nine enzymes of purine degradation present in  D. radiodurans , and (ii)  D. ficus  contains eight enzymes involved in nitrogen metabolism, including nitrate and nitrite reductases, that  D. radiodurans  lacks. Moreover, genes previously considered to be important to IR resistance are missing in  D. ficus  KS 0460, namely, for the Mn-transporter  nramp , and proteins DdrF, DdrJ and DdrK, all of which are also missing in  Deinococcus deserti . Otherwise,  D. ficus  KS 0460 exemplifies the  Deinococcus  lineage.   Electronic supplementary material  The online version of this article (doi:10.1186/s40793-017-0258-y) contains supplementary material, which is available to authorized users.

High-quality genome sequence of the radioresistant bacterium Deinococcus ficus KS 0460