English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Background  The physiologic characteristics of the cashmere trait and many of the differentially expressed genes relevant to hair cycling have been extensively studied, whereas genes involved in the prenatal development of hair follicles have been poorly investigated in cashmere goats. The aim of this study, therefore, was to quantify the time-course changes in the expressions of  TRα  and  CRABPII  genes in the fetal skin of Chinese cashmere goats at the multiple embryonic days (E70, E75, E80, E90, E100, E120 and E130) using real-time quantitative PCR (RT-qPCR).    Results  RT-qPCR showed that  TRα  was expressed at E70 with relatively high level and then slightly decreased (E75, E80, and E90). The highest expression of  TRα  mRNA was revealed at E130 ( P  > 0.05). The expression pattern of  CRABPII  mRNA showed an ‘up-down-up’ trend, which revealed a significantly highest expression at E75 ( P  < 0.05) and was down-regulated during E80 to E120 ( P  < 0.05) and mildly increased at E130, subsequently.    Conclusion  This study demonstrated that  TRα  and  CRABPII  genes expressed in different levels during prenatal development of cashmere. The present study will be helpful to provide the comprehensive understanding of  TRα  and  CRABPII  genes expressions during cashmere formation and lay the ground for further studies on their roles in regulation of cashmere growth in goats.    Electronic supplementary material  The online version of this article (doi:10.1186/s40781-015-0060-6) contains supplementary material, which is available to authorized users.

Expression patterns of TRα and CRABPII genes in Chinese cashmere goat skin during prenatal development