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New technology based firm (NTBF) survival and growth are connectedwith strategic partnering alliances and open innovation within technology clusters.Strategic partnerships in the biotechnology industry allow new technology basedfirms to gain a foothold in this high-cost, high-risk industry.In this article, we examine the impact of strategic partnerships and open innovationon the success of new biotechnology firms in Belgium by developing multiple casestudies of firms in regional biotechnology clusters.A longitudinal follow up of the Belgian biotech startup ecosystem is presented. Wefind that, despite their small size and relative immaturity, new biotechnology firmsare able to adopt innovative business models by providing R&D and services tolarger firms and openly cooperating with them through open innovation.Peer reviewe

journal of global entrepreneurship research

The interplay between new technology based firms, strategic alliances and open innovation, within a regional systems of innovation context. The case of the biotechnology cluster in Belgium