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Background  We present VREX, a free open-source Unity toolbox for virtual reality research in the fields of experimental psychology and neuroscience.    Results  Different study protocols about perception, attention, cognition and memory can be constructed using the toolbox. VREX provides a procedural generation of (interconnected) rooms that can be automatically furnished with a click of a button. VREX includes a menu system for creating and storing experiments with different stages. Researchers can combine different rooms and environments to perform end-to-end experiments including different testing situations and data collection. For fine-tuned control VREX also comes with an editor where all the objects in the virtual room can be manually placed and adjusted in the 3D world.    Conclusions  VREX simplifies the generation and setup of complicated VR scenes and experiments for researchers. VREX can be downloaded and easily installed from vrex.mozello.com    Electronic supplementary material  The online version of this article (doi:10.1186/s40359-017-0173-4) contains supplementary material, which is available to authorized users.

VREX: an open-source toolbox for creating 3D virtual reality experiments