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Ethnobotanical knowledge is important among tribal people, but much of the information is empirical due to the lack of scientific validation. The purpose of this study was to document the medicinal plants used by an ethnic group ( Yakkha ) at Chanuwa VDC of Dhankuta district in Nepal and to validate scientifically in the use of plants based on results of phytochemical, antimicrobial and antioxidant property analyses and available literature reports. Data were collected through interviews of the  Yakkha  people with the help of a semi-structured questionnaire and the guided field walk method. A total of 30 different medicinal plants were recorded along with their vernacular names (for few plants) used by the  Yakkha  community’s people. Literature review reveals that most of the plant species described herein have also been used in other countries, too. Among 30 plants selected for this study methanol extract of five ethno-medicinal plants viz.,  Dendrocnide sinuata ,  Solanum anguivi ,  Pogostemon cablin ,  Boehmeria platyphylla  and  Clerodendrum trichotomum  and ethanol extract of  C. trichotomum  were subjected for antibacterial and antioxidant properties. The antimicrobial activities were measured using the paper disc diffusion method. The antioxidant properties of plants were measured by DPPH and FRAP reduction assay. Among all extracts, ethanol extract of  C. trichotomum  and methanol extract of  B. platyphylla  displayed the highest antibacterial and antioxidant activities, respectively.

Scientific validation of medicinal plants used by Yakkha community of Chanuwa VDC, Dhankuta, Nepal