English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background  The scabies mite,  Sarcoptes scabiei,  is a parasitic arachnid and cause of the infectious skin disease scabies in humans and mange in other animal species. Scabies infections are a major health problem, particularly in remote Indigenous communities in Australia, where secondary group A streptococcal and  Staphylococcus aureus  infections of scabies sores are thought to drive the high rate of rheumatic heart disease and chronic kidney disease.    Results  We sequenced the genome of two samples of  Sarcoptes scabiei  var.  hominis  obtained from unrelated patients with crusted scabies located in different parts of northern Australia using the Illumina HiSeq. We also sequenced samples of  Sarcoptes scabiei  var.  suis  from a pig model. Because of the small size of the scabies mite, these data are derived from pools of thousands of mites and are metagenomic, including host and microbiome DNA. We performed cleaning and  de novo  assembly and present  Sarcoptes scabiei  var.  hominis  and var.  suis  draft reference genomes. We have constructed a preliminary annotation of this reference comprising 13,226 putative coding sequences based on sequence similarity to known proteins.    Conclusions  We have developed extensive genomic resources for the scabies mite, including reference genomes and a preliminary annotation.    Electronic supplementary material  The online version of this article (doi:10.1186/s13742-016-0129-2) contains supplementary material, which is available to authorized users.

Genomic resources and draft assemblies of the human and porcine varieties of scabies mites, Sarcoptes scabiei var. hominis and var. suis