English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In this paper, a class of virus infection models with CTLs response is considered. We incorporate an immune delay and two intracellular delays into the virus infection model. It is found that only incorporating two intracellular delays almost does not change the dynamics of the system, but incorporating an immune delay changes the dynamics of the system very greatly, namely, a Hopf bifurcation and oscillations can appear. Those results show immune delay dominates intracellular delays in some viral infection models, which indicates the human immune system has a special effect in virus infection models with CTLs response, and the human immune system itself is very complicated. In fact, people are aware of the complexity of the human immune system in medical science, which coincides with our investigating. We also investigate the global Hopf bifurcation of the system with the immune delay as a bifurcation parameter.

Stability and bifurcation analysis in a viral infection model with delays