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To solve the problem of CT image degradation, a double regularization CT image blind restoration reconstruction method was proposed. The objective function including both a clear image and point spread function was established. To avoid the over-smoothing phenomenon and protect the detail, the objective function includes two constraint regularization terms. They are total variation (TV) and wavelet sparsity respectively. The objective function was solved by the alternating direction multiplier method (ADMM), and the optimal solution was obtained. Firstly, the CT image blind restoration reconstruction was decomposed into two sub-problems: reconstructed image estimation and point spread function estimation. Furthermore, each sub-problem can be solved by the proximal alternating direction method of multipliers. Finally, the CT image blind restoration reconstruction was realized. The experimental results show that the proposed algorithm takes into account the degradation effect of projection data, and the proposed algorithm is superior to other existing algorithms in the subjective visual effect. At the same time, in the aspect of objective evaluation, the proposed algorithm improves the objective image quality metrics such as peak signal-to-noise ratio (PSNR), structural similarity index metric (SSIM), and universal image quality index (UIQI).

Double regularization medical CT image blind restoration reconstruction based on proximal alternating direction method of multipliers