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Background  Diaphragm paresis is common after cardiac surgery and may delay the weaning from the ventilator. Our objective was to evaluate diaphragm thickening during weaning and secondly the muscle thickness as a marker of myotrauma.    Methods  Patients undergoing elective cardiac surgery were prospectively included. Ultrasonic index of right hemidiaphragm thickening fraction (TF) was measured as a surrogate criterion of work of breathing. A TF < 20% was defined as a low diaphragm thickening. Measurements of TF were performed during three periods to study diaphragm thickening evolution defined by the difference between two consecutive time line point: preoperative ( D  − 1), during a spontaneous breathing trial (SBT) in the intensive care unit and postoperative ( D  + 1). We studied three patterns of diaphragm thickness at end expiration evolution from  D  − 1 to  D  + 1: > 10% decrease, stability and > 10% increase. Demographical data, length of surgery, type of surgery, ICU length of stay (LOS) and extubation failure were collected.    Results  Of the 100 consecutively included patients, 75 patients had a low diaphragm thickening during SBT. Compared to TF values at  D  − 1 (36% ± 18), TF was reduced during SBT (17% ± 14) and  D  + 1 (12% ± 11) ( P  < 0.0001). Thickness and TF did not change according to the type of surgery or cooling method. TF at SBT was correlated to the length of surgery (both  r  = − 0.4;  P  < 0.0001). Diaphragm thickness as continuous variable did not change over time. Twenty-eight patients (42%) had a > 10% decrease thickness, 19 patients (29%) stability and 19 patients (28%) in > 10% increase, and this thickness evolution pattern was associated with: a longer LOS 3 days [2–5] versus 2 days [2–4] and 2 days [2], respectively (ANOVA  P  = 0.046), and diaphragm thickening evolution (ANOVA  P  = 0.02). Two patients experience extubation failure.    Conclusion  These findings indicate that diaphragm thickening is frequently decreased after elective cardiac surgery without impact on respiratory outcome, whereas an altered thickness pattern was associated with a longer length of stay in the ICU. Contractile activity influenced thickness evolution.   Trial registry number  ClinicalTrial.gov ID NCT02208479    Electronic supplementary material  The online version of this article (10.1186/s13613-019-0521-z) contains supplementary material, which is available to authorized users.

Diaphragm thickening in cardiac surgery: a perioperative prospective ultrasound study