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Red-osier dogwood (ROD) extract contains a lot of polyphenols that have the potential for modulation of gut microbiota. However, little information is available about its prebiotic properties. This study investigated the impact of ROD polyphenol extract on the ileal microbiota with dietary supplementation of ROD polyphenol extract in a pig model. The data indicated that supplementation of ROD polyphenol extract significantly increased class  Bacilli , order  Lactobacillales  and family  lactobacillaceae . Within family  lactobacillaceae ,  Lactobacillus  was the main responder by increasing from 5.92% to 35.09%. Further analysis showed that ROD polyphenol extract improved two species  Lactobacillus delbrueckii  and  Lactobacillus mucus . The results of this study suggested that ROD polyphenol extract has the potential to play prebiotic role and confer health benefit through modifying gut microbiota.

Dietary supplementation of red-osier dogwood polyphenol extract changes the ileal microbiota structure and increases Lactobacillus in a pig model