English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Biofilm formation is a significant virulence factor in  Staphylococcus  ( S. )  aureus  strains causing subclinical mastitis in dairy cows. A role of environmental signals and communication systems in biofilm development, such as the  agr  system in  S. aureus , is suggested. In the context of multispecies biofilm communities, the presence of non- aureus  staphylococci (NAS) might influence  S. aureus  colonization of the bovine mammary gland, yet, such interspecies interactions have been poorly studied. We determined whether 34  S. chromogenes , 11  S. epidermidis , and 14  S. simulans  isolates originating from bovine milk samples and teat apices (TA) were able to affect biofilm formation and dispersion of  S. aureus , and if so, how isolate traits such as the capacity to regulate the  S. aureus agr  quorum sensing system are determinants in this process. The capacity of an  agr -positive  S. aureus  strain to form biofilm was increased more in the presence of  S. chromogenes  than in the presence of  S. simulans  and  S. epidermidis  isolates and in the presence of NAS isolates that do not harbor biofilm related genes. On the other hand, biofilm dispersion of this particular  S. aureus  strain was suppressed by NAS as a group, an effect that was more pronounced by isolates from TA. Furthermore, the observed effects on biofilm formation and dispersion of the  agr -positive  S. aureus  strain as well as of an  agr -negative  S. aureus  strain did not depend on the capacity of NAS to repress the  agr  system.   Supplementary Information  The online version contains supplementary material available at 10.1186/s13567-021-00985-z.

Bovine-associated non-aureus staphylococci suppress Staphylococcus aureus biofilm dispersal in vitro yet not through agr regulation